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Result(s) for "Muscle"

	Project Title	Status	Abstract
1.	Neural expression of MRF4 in Xenopus laevis	Current	Skeletal muscle embryonic development is regulated by many genes, including one called MRF4. In mammals, MRF4 is expressed only in myogenic cells, but in the frog Xenopus laevis, we have observed MRF4 expression in embryonic neural structures as well. This project aims to suppress MRF4 expression in the embryo via antisense morpholino oligonucleotide injection and then assess abnormalities in muscle and neural development anatomically and at the level of gene transcription. Techniques used will include in situ hybridization, RT-PCR, and frozen sectioning of embryos.